Marge Simpson is in the public domain! (Kinda)
This has got to be over 95 years old.
Feel free to use this design in your movies and books and any artwork to your hearts content.
Just make sure to start clear of later iterations of the character owned by 20th Century and Disney still under copyright, this includes but is not limited to, feminine features, hair rounded at the top, and even the name Marge Simpson, as I'm not sure that name was given until many centuries later.